Drugs of Today -TRBIO510

Examines the intricate functional signaling mechanisms that underlie common and blockbuster drug actions

Course Director: Laura Bohn
Term: Spring (every other year)
Credits: 3.0

COURSE DESCRIPTION
This course is proposed as an advanced molecular pharmacology course for graduate students. The goal of this course is to examine the intricate functional signaling mechanisms that underlie common and blockbuster drug actions. We will evaluate pharmacological principles in the context of cellular signaling mechanisms that underlie conventional and unconventional drug actions associated with current therapeutic treatments. The focus of the course will be to showcase the intricacy of cellular signaling and how this can be manipulated in order to affect whole body physiological responses. Diseases and drugs will be chosen to reflect the state-of-the-art in pharmacotherapies targeting cellular signaling mechanisms. The goal of this course is not to teach, per se, the mechanism, but to provide the students with advanced knowledge in order to develop novel approaches for considering cellular targets in treating human disease.

There are complementary courses taught at Scripps Research that cover drug development and drug actions in humans (Medicinal Chemistry, Drug Discovery and Development: Translating basic research discoveries into novel therapeutics, and Molecular Medicine, for example). This course differs in that it showcases current therapeutics for how they utilize molecular mechanisms at the cellular level to produce physiological effects.

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