Brendan Dwyer, Ph.D.
Doctoral Thesis: Chemoproteomic Tools for Profiling Bioactive Small Molecules: From De Novo Photopharmacology to Cysteine-Reactive Covalent Drugs to Natural Product Target Identification
Description of Research Focus: Dwyer developed chemoproteomic tools to study how drugs work inside cells and to find new drug targets for various diseases, especially cancer.
Undergraduate Institution: Willamette University
Noteworthy Publications:Total Synthesis and Target Identification of the Curcusone Diterpenes, Journal of the American Chemical Society (2021); Chemoproteomics‐Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism, Angewandte Chemie International Edition (2020)
Looking Back: "At Scripps, I discovered my passion for chemoproteomic-enabled drug discovery and will be forever grateful for the wonderful opporuntities, memory, and support from my advisor, wife, colleagues, collaborators, family, and friends. Thank you!"
Next Steps: "My next step will be a postdoctoral position to further expand my techniques and expertise to help develop better therapeutics and diagnostics for cancer and neurodegenerative diseases."
Be sure to join us at 10 a.m. PDT on Friday, May 20 for our Commencement Ceremony Livestream! Dwyer's advisor and mentor, Prof. Alexander Adibekian, will deliver a few words about his graduate experience, and viewers can learn about our 47 other 2022 graduates, who are now setting out to build careers that will profoundly impact the future of biomedical research.
