Andrew Shuparski, Ph.D.
Doctoral Thesis: PD‐1 Checkpoint Blockade Disrupts CD4 T Cell Regulated Adaptive B Cell Tolerance
Description of Research Focus: Shuparski's research used single cell analysis to define the T cell driven mechanisms behind PD-1 as a checkpoint of adaptive tolerance.
Undergraduate Institution: University of Western Ontario
Noteworthy Publications: Single cell qtSEQ: cell-indexed quantitative and targeted RNA sequencing for sorted rare lymphocyte subpopulations, STAR Protocols (2022)
Looking Back: "Looking back on my time in graduate school I appreciate how the do-it-yourself approach of the McHeyzer-Williams group enabled our lab to develop a bespoke approach to single cell genomics, which we applied to uncover lots of interesting germinal center immunology. I also appreciate all the really fantastic people I met along the way and how close Scripps is to some solid surf breaks."
Next Steps: "After defending my thesis I joined the biotech company Immunai in NYC as a Systems Immunologist. Here I build off of the skill sets I learned at Scripps by using multi-model single cell technologies to identify novel therapeutic approaches."
Be sure to join us at 10 a.m. PDT on Friday, May 20 for our Commencement Ceremony Livestream! Shuparski's advisor and mentor, Prof. Michael Mcheyzer-Williams, will deliver a few words about his graduate experience, and viewers can learn about our 47 other 2022 graduates, who are now setting out to build careers that will profoundly impact the future of biomedical research.
