Stephan Spangenberg, PhD
Doctoral Thesis: Identification of Novel Mechanisms Regulating Expression of PD-L1 and Other Immune Checkpoint Proteins Using Chemical Biology Approaches
Research Focus: Spangenberg used chemical biology approaches to study regulation of immune checkpoint protein expression.
Undergraduate Institution: University of California, San Diego
Noteworthy Publications: Hydroxyproline Enhances IFN-γ Induced PD-L1 Expression and Inhibits Autophagic Flux, Cell Chemical Biology (2023); HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins, Cell Chemical Biology (2020); Protocol for High-Throughput Compound Screening Using Flow Cytometry in THP-1 Cells, STAR Protocols (2021)
Honors and Awards: Student Poster Competition Winner, SLAS International Conference (2022); Tony B. Travel Award, SLAS International Conference (2022)
Looking Back: "My success in graduate school would not have been possible without my great mentor, and my colleagues and friends."
Next Steps: "I am currently a postdoctoral scholar at UCSF, working with Dr. David Toczyski. I am studying regulation of the cell cycle by ubiquitin ligases."
Join us at 10 a.m. PDT on Friday, May 17, 2024 for our Commencement Ceremony Livestream! Spangenberg wil be introduced by a faculty member, who will deliver a few words about his graduate experience. Viewers will also learn about our many other 2024 graduates, who are now setting out to build careers that will profoundly impact the future of biomedical research.
